Lost connection between iTunes and iTunes folders -- HELP?

We are a three iPod home, but my son just purchased an iPod Touch.  While I was at work, he decided to set it up on our home computer without me.  When I got home, I brough up iTunes to sync up my iPod to new podcast downloads, and iTunes did not recognize my iPod and it did not show any content within my iTunes music or podcast libraries.  When I pull up Windows Explorer, all of my music and podcast files are still present on my hard drive, but for some reason, iTunes is coming up as if nothing is loaded.Any suggestions on how I reconnect my iTunes software to my iTunes folders?  ...and, yes, the iTunes Media Folder Location is set to the correct folder on my hard-drive.Any help would be appreciated.  Thanks!